Using immunomarkers of axonal pathology [β-amyloid precursor protein (β-APP) and apoptotic marker fractin], we tested the hypothesis that widespread (diffuse) axonal injury occurs in the gliotic ...

Axons, the fundamental output structures of neurons, play a pivotal role in transmitting electrical signals over long distances without attenuation in the nervous system. Beyond their classical role ...

visualizes axons in an area-specific maturation patternin human fetal brain; visualizes aberrantly sprouting axons in neuriticplaques derived from cortico-cortical fibers in A.D. and identifies loss ...

Blood biomarkers at disease onset may help predict relapse-associated worsening and progression independent of relapse ...

Neurotransmitters are key for synaptic transmission at axon terminals, but their transport modalities remain debated. This ...

This study uncovers how oligodendroglial lipid metabolism supports myelin homeostasis and axonal function under metabolic ...

Stock of Applied Therapeutics, Inc. surges as FDA skips AdCom for AT-007 in galactosemia. Read more on recent developments ...

Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...

To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...

Update on FDA's Applied Therapeutics, Inc. decision to remove advisory panel for govorestat review in treating galactosemia.

A new study from the Imperial College of London found that more expensive bike helmets do not necessarily provide more safety ...