Vascular smooth muscle cell membranes were prepared from neonatal piglet aortas by homogenization, low speed centrifugation to remove intact cells and ultracentrifugation. Aliquots of the membrane ...

Alpha-1 adrenergic receptors (α1-ARs) are a subset of G protein-coupled receptors that play a pivotal role in cardiovascular homeostasis. While traditionally recognised for their involvement in ...

The following studies were undertaken to develop a cultured uterine myocyte model which would allow further clarification of the adrenergic signal transduction mechanisms utilized by these myocytes.

In a new study, researchers report that a class of heart medications called beta-blockers can have a helpful, or harmful, effect on the heart, depending on their molecular activity. In a new study, ...

Individuals with some forms of heart failure are treated with drugs that are known as beta-blockers because they target proteins known as beta-adrenergic receptors (beta-ARs). Now, a potential ...

Epinephrine 0.15mg (1:2000); prefilled auto-injector; contains sulfites. Epinephrine acts on both alpha- and beta-adrenergic receptors. Through its action on alpha-adrenergic receptors, epinephrine ...

Recent clinical studies have suggested that phenylacetylglutamine (PAGln), a novel gut microbial metabolite, can mechanistically modulate patients' risk of developing cardiovascular disease (CVD) and ...

The physiological regulation of color changes in reptiles as studied in the lizard, Anolis carolinensis, is discussed. In Anolis, the ability to adapt to a background is dependent upon the level of ...