资讯
为解决 ADSC-Exos 调节炎症细胞参与伤口愈合机制不明的问题,解放军总医院第四医学中心的研究人员探究其如何调节巨噬细胞促进伤口愈合。结果发现其通过调节巨噬细胞极化和 IL-33 释放发挥作用,为组织修复研究提供新视角,值得科研读者一读。
而ADSC外泌体干预后,这些指标均恢复至接近正常水平,证实其能有效逆转高糖诱导的细胞功能障碍。 【ADSC exosomes regulated Keap1/Nrf2 axis to reduce oxidative stress】 机制研究揭示,ADSC外泌体通过下调Keap1表达,促进Nrf2核转位,进而上调HO-1和GPX4等抗氧化酶的表达。
然后,将ADSC-exos完全包裹到ECM水凝胶中,制备了ECM@exo。 如前所述,一旦注射到伤口部位,ECM@exo溶液就可以在生理温度 (近37°C)下形成水凝胶。
同济大学江华、李宇飞团队在Bioactive Materials (IF 18.9)发表题为“Bioinspired engineering ADSC nanovesicles thermosensitive hydrogel enhance autophagy of dermal papilla cells ...
The application of ADSC-Exos represents a promising therapeutic strategy for diabetic wound healing. By enhancing autophagy, ADSC-Exos improve the function of epidermal cells, facilitating rapid ...
ABU DHABI, 5th May, 2025 (WAM) -- The Abu Dhabi Sports Council (ADSC) and Abu Dhabi Cycling Club (ADCC) have signed two partnership agreements with the National Health Insurance Company – Daman ...
The Executive Director, African Development Studies Center (ADSC), Mr Victor Walsh Oluwafemi, has called for strict adherence to international standards of public financial management to uphold ...
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