The adenosine pathway is increasingly recognized as one of the most important drivers in decreasing the immune response in cancer through upregulation of checkpoints, metabolic downregulation of T ...

This article is based on a poster originally authored by Philip Rawlins, Jim Reid, William Lee, Holly Madden, Soumya Dhanavade, James Craswell, Satya Bhamidimarri, Anna Hopkins, Joe Mason, Marieke ...

Scientists from The Scripps Research Institute have determined the structure of an adenosine receptor that plays a critical role in a number of important physiological processes including pain, ...

The new Scripps Research study reveals the structure of the human A2A adenosine receptor (sometimes referred to as the "caffeine receptor"), shedding light on the large and medically important family ...

The adenosinergic system, principally mediated by four subtypes of G-protein-coupled adenosine receptors (A1, A2A, A2B and A3), plays a pivotal role in the regulation of immune responses.

GPCRs are the largest receptor class, affecting almost every aspect of human physiology, with 35% of all approved drugs acting on GPCRs. They regulate sensory and neuronal signaling, as well as a ...

Researchers have found that blood flow in the brain capillaries, which is important for oxygen/nutrient delivery and waste removal, was increased during rapid eye movement sleep in mice. Adenosine A2a ...

Marvel Biosciences Corp. (TSXV: MRVL) and its wholly owned subsidiary, Marvel Biotechnology Inc. (collectively the "Company" ...

Portage Biotech Inc. (NASDAQ:PRTG) on Thursday presented new preclinical data for PORT-7 (TT-4), a selective Adenosine A2B receptor inhibitor, at the 2025 European Lung Cancer Congress. The new data ...

Portage Biotech Inc. (NASDAQ:PRTG) stock traded higher on Monday, with a session volume of 4.49 million compared to the average of 1.2 million, according to data from Benzinga Pro. On Monday, the ...