No Kittle means the 49ers will be down three All-Pros on offense. The club figured to rely heavily on him while McCaffrey and ...

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

San Francisco 49ers tight end George Kittle did not practice on Thursday, putting his Week 3 status in question. Kittle is ...

The San Francisco 49ers could be without another key offensive player this week after All-Pro tight end George Kittle missed ...

Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

If Ward is unable to go, all signs point to rookie second-round pick Renardo Green getting the start as the 49ers’ nickel ...

Purdy still hasn't entirely shaken the "system" quarterback label and other denigrations. A chance for his rebuttal is now ...

Matt Lively reports on two more key 49ers all-star players suffering from injuries who did not practice Thursday.

The spread has moved one point in the Rams’ direction since Monday, likely because of the 49ers’ recent injury news ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco ...

Soft-tissue injuries are often prevalent early in the NFL season because there is less contact during training camp and ...

The San Francisco 49ers started off Week 3 on the right foot. After absences and limited participations littered their first ...