Injuries derailed the San Francisco 49ers' 2024 season, but none had a more significant impact on the offense than the loss of star running back Christian McCaffrey.

The San Francisco 49ers are in a tough spot with Jauan Jennings contract negotiations after placing 2 WRs on injured lists ...

This year it will largely be the same group with a smattering of new veterans and a couple of rookies entering training camp.

How will the fatigue index affect the 49ers in 2025? That remains to be seen, but this season will be centered around the ...

The 49ers made it clear through their offseason that they have plenty of confidence in their offensive line. They lost ...

Another notable designation is offensive lineman Ben Bartch, who will begin training camp on the active/non-football injury ...

Head coach Kyle Shanahan didn't seem concerned about the San Francisco 49ers injury situation after 15 players missed ...

The 49ers’ defensive makeover and a couple contract situations are among 10 storylines to watch when training camp opens ...

The San Francisco 49ers have released a former All-Pro talent in a "surprising" roster move ahead of the first practice of training camp.

The 49ers placed six players on their active/physically unable to perform list Friday, including wide receivers Brandon Aiyuk ...

What's wrong with the 49ers? Injuries are only part of equation The NFL Week 8 notebook takes a closer look at the 49ers' mounting issues, Tua Tagovailoa's return to action and more throughout the ...

The Green Bay Packers will be without two defensive starters for Sunday’s game against the San Francisco 49ers, but the Niners have much, much larger injury concerns.