Isothiocyanate - Wikipedia
网页Isothiocyanate. General structure of an isothiocyanate. In organic chemistry, isothiocyanate is a functional group as found in compounds with the formula R−N=C=S. Isothiocyanates are the more common isomers of thiocyanates, which have the formula R−S−C≡N.
Isothiocyanates | Linus Pauling Institute | Oregon State University
网页Using a primary rat hepatocyte-based model, both aliphatic (e.g., sulforaphane, AITC) and aromatic (e.g., BITC, PEITC) isothiocyanates (at 20-40 μM) have been found to downregulate CYP3A2 mRNA expression, as well as the activity of benzyloxyquinoline debenzylase, a marker of CYP3As (22).
Isothiocyanates: An Overview of Their Antimicrobial Activity …
网页2018年3月9日 · In order to identify phytochemical compounds that preserve the natural intestinal microflora and ensure pathogen strain growth inhibition, Kim and Lee evaluated the antimicrobial activity of phenethyl isothiocyanate (PEITC) purified from Sinapis alba seed oil against pathogenic Clostridium species .
Isothiocyanate - an overview | ScienceDirect Topics
网页Isothiocyanates (ITCs) are bioactive products resulting from enzymatic hydrolysis of glucosinolates (GLs), the most abundant secondary metabolites in the botanical order Brassicales, and have the antimicrobial activity against foodborne and plant pathogens (Romeo et al., 2018).
Isothiocyanates: translating the power of plants to people
网页Herein, clinical trials employing two isothiocyanates, sulforaphane (SFN; 1-Isothiocyanato-4-(methylsulfinyl) butane) and phenethyl isothiocyanate (PEITC; 2-isothiocyanatoethylbenzene) that are isolated principally from broccoli and watercress, respectively, are summarized and discussed.
A Comparative Review of Key Isothiocyanates and Their Health …
网页2024年3月7日 · This comprehensive review aims to consolidate the current understanding of Moringa isothiocyanates, mainly 4- [ (α-L-rhamnosyloxy) benzyl] isothiocyanate), comparing this compound with other well-studied isothiocyanates such as sulforaphane and phenyl ethyl isothiocyanates.
Isothiocyanates in medicine: A comprehensive review on …
网页In recent years, isothiocyanates (ITCs), bioactive compounds primarily derived from Brassicaceae vegetables and herbs, have gained significant attention within the biomedical field due to their versatile biological effects. This comprehensive review provides an in-depth exploration of the therapeuti ….
Isothiocyanate - an overview | ScienceDirect Topics
网页Isothiocyanates is a potential group of bioactive compounds including phenethyl isothiocyanate, benzyl isothiocyanate, sulforaphane and have been used for the treatment of various neoplasms including BC (Li et al., 2017a, 2017b).
Isothiocyanates in Food - SpringerLink
网页2021年8月10日 · Isothiocyanate is an enzymatic hydrolysate of glucosinolates that are abundant in Brassicaceae or Cruciferae crops such as broccoli, radish, and cabbage. In addition to application in food products, isothiocyanates can effectively prevent DNA damage and cancer caused...
Biological targets of isothiocyanates - ScienceDirect
网页2011年9月1日 · Direct and indirect effects of isothiocyanates in biological systems. Isothiocyanates cross the plasma membrane of cells by passive diffusion and rapidly accumulate within cells. A primary reaction, catalysed by glutathione-S-transferases, is with thiol tripeptide glutathione (γGlu-Cys-Gly).