Thiazolidinedione - Wikipedia
网页The thiazolidinediones / θaɪ.əˌzoʊlɪdiːnˈdaɪ.oʊn /, abbreviated as TZD, also known as glitazones after the prototypical drug ciglitazone, [1] are a class of heterocyclic compounds consisting of a five-membered C 3 NS ring.
噻唑烷二酮 - 百度百科
网页噻唑烷二酮（TZD），口服降糖药（格列酮类），为胰岛素增敏剂，通过增加外周组织对胰岛素的敏感性、改善胰岛素抵抗而降低血糖，并能改善与胰岛素抵抗有关的多种心血管危险因素。. 该类药物应用过程中须密切注意肝功能。.
List of Thiazolidinediones (glitazones) - Drugs.com
网页Thiazolidinediones (also called glitazones) are a class of medicines that may be used for the treatment of type 2 diabetes. They are a type of oral hypoglycemic (a medicine that …
Home | Minnesota Toward Zero Deaths
网页Minnesota TZD saves lives by bringing together Education, Enforcement, Emergency Medical and Trauma Services, Engineering—and more!
Thiazolidinediones - StatPearls - NCBI Bookshelf
网页2023年2月20日 · Thiazolidinediones (TZDs) are insulin sensitizers that act on intracellular metabolic pathways to enhance insulin action and increase insulin sensitivity in critical tissues. [4] TZDs also increase adiponectin levels, decrease hepatic gluconeogenesis, and increase insulin-dependent glucose uptake in muscle and fat.
Thiazolidinediones in the treatment of type 2 diabetes mellitus
网页2024年5月20日 · The thiazolidinediones increase insulin sensitivity by acting on adipose, muscle, and, to a lesser extent, liver to increase glucose utilization and decrease glucose production. One thiazolidinedione (pioglitazone) is currently available in the United States.
Thiazolidinediones: the Forgotten Diabetes Medications - PMC
网页2019年11月27日 · Thiazolidinediones (TZDs) are the only pharmacologic agents that specifically treat insulin resistance. The beneficial effects of TZDs on the cardiovascular risk factors associated with insulin resistance have been well documented. TZD use has been limited because of concern about safety issues and side effects. Recent Findings.
Efficacy and safety of thiazolidinediones in diabetes patients with ...
网页2017年5月11日 · The thiazolidinediones (TZDs) (rosiglitazone and pioglitazone) are activated receptor gamma (PPAR-γ) antidiabetic agents, and are mainly metabolized by liver. They do not require dose...
糖尿病的非胰岛素药物总结 - 知乎 - 知乎专栏
网页在我国 T2DM 患者中开展的临床研究结果显示，TZD 可使 HbA1c下降 0.7%~1.0%（去除安慰剂效应后）。. TZD 具有促进葡萄糖利用和促进脂肪合成的作用，所以体重增加是其主要不良反应。. TZD的使用与骨折、心力衰竭、肝损风险增加相关。. 所以心力衰竭[纽约心脏学会 ...
Thiazolidinediones (TZDs) | DiaTribe
网页Thiazolidinediones (TZDs), also known as glitazones, are an older type of medication that people with type 2 diabetes can use to lower blood sugar levels by reducing insulin resistance. See All Thiazolidinediones (TZDs) News.
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