Spinocerebellar ataxia type 3 | About the Disease | GARD
网页Spinocerebellar ataxia 3 (SCA3) is a rare, inherited form of ataxia. Signs and symptoms may begin between childhood and late adulthood and vary greatly. Symptoms may include slowly progressive clumsiness in the arms and legs; a manner of walking (gait) that may be mistaken for drunkenness; difficulty speaking and swallowing; impaired eye ...
Spinocerebellar ataxia type 3 - MedlinePlus
网页Spinocerebellar ataxia type 3 (SCA3) is a condition characterized by progressive problems with movement. Explore symptoms, inheritance, genetics of this condition.
Spinocerebellar Ataxia Type 3 - GeneReviews® - NCBI Bookshelf
网页1998年10月10日 · Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), is characterized by progressive cerebellar ataxia and variable findings including pyramidal signs, a dystonic-rigid extrapyramidal syndrome, significant peripheral amyotrophy and generalized areflexia, progressive external ophthalmoplegia, action …
SCA3/MJD - National Ataxia Foundation
网页SCA3 (also known as Machado-Joseph Disease) is one of the most common types of Spinocerebellar Ataxias. This webinar covers the causes and symptoms of SCA3/MJD, the typical diagnostic journey for those affected, and what to expect for clinical care.
Spinocerebellar Ataxias including Machado-Joseph Disease
网页2024年7月19日 · SCA3 (also known as Machado-Joseph disease) is characterized by slowly progressive clumsiness in the arms and legs, a staggering or lurching gait, difficulty with speech and swallowing, impaired eye movements sometimes accompanied by double vision or bulging eyes, and lower limb spasticity.
Spinocerebellar Ataxia (SCA): Symptoms, Causes & Types - Cleveland Clinic
网页2022年8月29日 · Spinocerebellar ataxia (SCA) comprises more than 40 types of similar inherited brain disorders. SCA affects your cerebellum, a part of your brain vital to physical movement. It causes problems with coordination and movement. There’s no cure, so treatment aims to relieve symptoms and improve function.
Machado-Joseph Disease: Symptoms and Treatment - Verywell …
网页2023年8月16日 · Machado-Joseph disease (MJD), also known as spinocerebellar ataxia type 3, or SCA3, is an inherited ataxia disorder. Ataxia can affect muscle control, resulting in a lack of balance and coordination. Specifically, MJD causes a progressive lack of coordination in the arms and legs.
Spinocerebellar Ataxia - StatPearls - NCBI Bookshelf
网页2023年9月15日 · Spinocerebellar ataxia (SCA) is a progressive neurodegenerative inherited (autosomal dominant) heterogeneous disease that mainly affects the cerebellum. SCA is a subset of hereditary cerebellar ataxia and is a rare disease.
Spinocerebellar ataxia type 3 (SCA3) | MedLink Neurology
网页1996年7月22日 · Spinocerebellar ataxia type 3 (SCA3) is the most commonly inherited autosomal dominant ataxia. It is mediated by an expanded triplicate nucleotide repeat that encodes for mutant ataxin-3 protein. Gait ataxia is the most common presenting symptom.
Orphanet: Spinocerebellar ataxia type 3
网页Spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease, is the most common subtype of type 1 autosomal dominant cerebellar ataxia (ADCA type 1; see this term), a neurodegenerative disorder, and is characterized by ataxia, external progressive ophthalmoplegia, and other neurological manifestations.
- 某些结果已被删除