Amidine - Wikipedia
网页Amidines are organic compounds with the functional group RC (NR)NR 2, where the R groups can be the same or different. They are the imine derivatives of amides (RC (O)NR 2). The simplest amidine is formamidine, HC (=NH)NH 2. Examples of amidines include: DBU. diminazene. benzamidine. Pentamidine. Paranyline. Preparation.
Amidine synthesis - Organic Chemistry Portal
网页NaI-catalyzed direct condensation of sulfonamides and formamides enables N -sulfonyl formamidine synthesis without hazardous reagents or transition-metal catalysts. The green methodology features high atom economy, operational simplicity, and good tolerance with diverse functional groups.
Fast and facile synthesis of amidine-incorporated degradable
网页2024年7月9日 · Here we develop a one-pot, tandem multi-component reaction based on the rationally designed amine–thiol–acrylate conjugation, which enables fast (1 h) and facile room-temperature synthesis of...
网页Amidines through one-pot three component reactions. Reaction of an isocyanide (1 mmol), an aldehyde (1 mmol), and an amine (2 mmol) using 1 mol% of molecular iodine in methanol, gave amidines 95 in good yields (Scheme 45).75. Scheme 45. One-pot reaction for the formation of amidines 95. 4.11.
Amidines - an overview | ScienceDirect Topics
网页Amidines are nitrogen compounds that can act as bidentate ligands in coordination chemistry, often used to stabilize unusual scandium and yttrium compounds. AI generated definition based on: Comprehensive Coordination Chemistry II, 2003. About this page. Add to Mendeley Set alert. You might find these chapters and articles relevant to this topic.
A General Strategy to Install Amidine Functional Groups Along the ...
网页2022年12月5日 · Amidines are a structural surrogate for peptide bonds, yet have received considerably little attention in peptides due to limitations in existing methods to access them. The synthetic strategy developed in this study represents the first robust and general procedure for the introduction of amidines into the peptide backbone.
Amidine Definition & Meaning | Merriam-Webster Medical
网页The meaning of AMIDINE is any of various strong monobasic compounds containing an amino and an imino group attached to the same carbon atom and having the general formula RC(=NH)NH2.
Amidine containing compounds: Antimicrobial activity and its …
网页2024年8月15日 · Researchers commonly modify molecules containing amidine or incorporate amidine into existing antimicrobial agents to enhance their pharmacological attributes and combat antimicrobial resistance. This comprehensive review consolidates the current knowledge on amidine-containing compounds, elucidating their antimicrobial mechanisms and ...
Amidine - chemeurope.com
网页Amidines are a class of oxoacid derivatives . Weighing the right way. Safe Weighing Range Ensures Accurate Results. What is the Sensitivity of my Balance? The oxoacid from which an amidine is derived must be of the form R n E (=O)OH, where R is a substituent.
Amidines - DrugBank Online
网页A histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion. An antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis. An alpha-2A adrenergic receptor agonist used to treat ADHD.